منابع مشابه
Is surgery necessary for 'mild' or 'asymptomatic' hyperparathyroidism?
A large majority of the currently diagnosed patients with hyperparathyroidism (PHPT) are mild or asymptomatic, mainly women after menopause. Following the debate held at the 16th European Congress of Endocrinology in Wroclaw (Poland) from May 3-7, 2014, arguments are here presented by a surgeon and a medical practitioner considering these situations rather have to profit from surgery, or simply...
متن کاملAsymptomatic primary hyperparathyroidism.
The clinical profile of primary hyperparathyroidism (PHPT) as it is seen in the United States and most Western countries has evolved significantly over the past half century. The introduction of the multichannel serum autoanalyzer in the 1970s led to the recognition of a cohort of individuals with asymptomatic hypercalcemia, in whom evaluation led to the diagnosis of PHPT. The term "asymptomati...
متن کاملAsymptomatic and Recurrent Hyperparathyroidism
Symptomatic Disease Bone disease in its florid form, osteitis fibrosa cystica generalizata, is now rarely seen. In 1947 Norris (1) found an incidence of this condition of 91% in those with a parathyroid adenoma. The earliest changes can be detected by X-rays of the hands where subperiosteal erosions can be detected in the phalanges (especially radial aspect of the middle phalanges) and terminal...
متن کاملRandomized controlled clinical trial of surgery versus no surgery in patients with mild asymptomatic primary hyperparathyroidism.
Parathyroidectomy is the definitive therapy for patients with symptomatic primary hyperparathyroidism. However, the role of surgery in mild asymptomatic primary hyperparathyroidism remains controversial. Accordingly, we conducted a prospective, randomized, controlled clinical trial of parathyroidectomy to determine the benefits of surgery vs. adverse effects of no surgery. Fifty-three patients ...
متن کاملSurgery or surveillance for mild asymptomatic primary hyperparathyroidism: a prospective, randomized clinical trial.
CONTEXT It is unclear whether patients with asymptomatic primary hyperparathyroidism (PHPT) do better with parathyroidectomy (PTx) as compared with conservative medical management. OBJECTIVE The aim of the study was to evaluate the beneficial effect of PTx vs. conservative management in patients with mild asymptomatic PHPT. DESIGN We conducted a prospective, randomized study. SETTING The ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1980
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.281.6238.520-e